GuoQiang Chen



George Guo-Qiang CHEN


Tsinghua University

School of Life Sciences

MOE Changjiang Scholar Professor



Education and Work Experience


1981-1985    B.Sc., South China University of Technology, China

1985-1989    Ph.D., Graz University of Technology, Austria

1990-1994    Postdoc, University of Nottingham (UK) and University of Alberta (Canada)

1994-1997    Associate Professor, Tsinghua University

1997-Present  Professor, Tsinghua University


Research areas and interests


He has been focusing his research on microbial materials polyhydroxyalkanoates (PHA) metabolic engineering and PHA biomaterials application since 1986. After joining Tsinghua University in 1994, he has been actively promoting the microbial Bio- and Material Industries in China. Professor Chen has more than 30 years of R&D experiences on microbial physiology, microbial PHA production and applications, has published over 200 international peer reviewed papers with over 8000 citations (H-Index 47) as reported in Web of Science.




Good Teacher and Friend to Graduate Students of Tsinghua Univ2001-2006

Mei Yiqi Award, Tsinghua University, 2007-2010

2nd Class China National Invention Award2002

Outstanding Young Researcher Award2003

Mao Yisheng Science and Technology Award2003

Silver award, Internationale Ausstellung, Ideen, Erfindungen und Neuheiten, Nürnberg, Germany2003

8th Young Chinese Scientific Achievement Award2004

Cheungkong ScholarMinistry of Education, 2004

Board of Directors for China Biotechnology Association2006-Present


Selected Publication


  1. Dong CL, Webb WR, Peng Q, Tang JZ, Forsyth NR, El Haj AJ and Chen GQ. A 3D collagen hydrogels stem cell tissue engineered formulation basing on growth factor phospholipid complex loaded PHBHHx nanoparticles. Journal of Biomedical Materials Research Part A 103 (2015) 282-288
  2. Yin Jin, Chen GQ. Halomonas spp, a Rising Star for Industrial Biotechnology. Biotechnology Advance 10.1016/j.biotechadv.2014.10.008 (2015)
  3. Guo YY, Shi ZY, Fu XZ, Chen JC, Wu Q and Chen GQ. Enhance General Circular DNA Construction Efficiency by Circumventing Long-Standing Contradictions among Ligation/Assembly and Transformation Steps. Microbial Cell Factories 2015, 14:18
  4. Yin J, Wang H, Gao X, Fu XZ, Wu Q and Chen GQ. Effects of chromosomal gene copy number and locations on polyhydroxyalkanoates synthesis by Escherichia coli and Halomonas sp. Appl Microbiol Biotechnol 99 (2015) 5523–5534
  5. Lv L, Ren YL, Chen JC, Wu Q and Chen GQ. Application of CRISPRi for Prokaryotic Metabolic Engineering Involving Multiple Genes, A Case Study: Controllable P(3HB-co-4HB) Biosynthesis. Metabolic Engineering 29 (2015) 160–168
  6. Meng DC, Wang Ying, Shen Rui, Chen JC, Wu Q and Chen GQ. Production of Poly(3-Hydroxypropionate) and P(3_Hydroxybutyrate-co-3-Hydroxypropionate) from Glucose by Engineered E. coli. Metabolic Engineering 29 (2015) 189–195
  7. Jiang XR, Wang H, Shen R, Chen GQ.  Engineering the Bacterial Shapes for Enhanced Inclusion Bodies Accumulation. Metabolic Engineering 29 (2015) 227-237
  8. Guo YK, Dong JK, Zhou T, Li TY, Zhang WM, Wang LH, Auxillos J, Shen Y, Luo YS, Zheng YJ, Lin JW, Chen GQ, Wu QY, Cai YZ, Dai J
  9. Chen GQ, Hajnal I, Ma YM, Wu H, Ye JW. Engineering the bacterial synthesis mechanism for diversifying polyhydroxyalkanoates. Trends in Biotechnology 33 (2015) 565-574
  10. Chen GQ, Hajnal I. The “PHAome”. Trends in Biotechnology 33 (2015) 559-564



Lab of Microbiology, School of Life Sciences,Tsinghua University

Tsinghua University, Beijing 100084


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