Junbiao DAI

Junbiao DAI


Tsinghua University

School of Life Sciences

Principle Investigator


Education and Work Experience


1994-1997    B.Sc., Nanjing University

1997-2000       M.S., Department of Biological Science and Biotechnology, Tsinghua University

2000-2006       Ph.D., Iowa State University, USA

2006-2011       Postdoctoral fellow, Johns Hopkins University, USA

2011-present   Associate professor, School of Life Sciences, Tsinghua Univeristy


Research areas and interests


The Dai lab uses budding yeast as model organism to study the function of chromatin with emphasis on histone modifications. In addition, his lab is synthesizing the yeast chromosome XII as a part of the international collaborative project (the Sc2.0 project) and developing technologies for synthetic biology. He has published over 20 papers in major scientific journals and awarded several patents.




Research Excellent Award from Iowa State University (2006)

Albert Lehninger Award from Johns Hopkins University School of Medicine (2011)  Awarded the Young Thousand Talent Program (2011)


Selected Publication


Guo YK, Dong JK, Zhou T, Auxillos J, Li TY, Zhang WM, Wang LH, Shen Y, Luo YS, Zheng YJ, Lin JW, Chen GQ, Wu QY, Cai YZ* and Dai JB*, YeastFab: the design and construction of standard biological parts for metabolic engineering in Saccharomyces cerevisiae. Nucleic Acids Res. 2015, 43(13):e88. (*Co-corresponding author)

Zhang HS, Li J, Hou S, Wang GC, Jiang MJ, Sun CH, Hu XB, Zhuang FF, Dai ZF, Dai JB* and Xi JZ*, Engineered TAL Effector modulators for the large-scale gain-of-function screening. Nucleic Acids Res. 2014, 42(14): e114 (*Co-corresponding author)

Dai JB*, Hyland EM*,. Yuan DS, Huang HL, Bader JS and Boeke JD. Probing Nucleosome Function: A Highly Versatile Library of Synthetic Histone H3 and H4 Mutants. Cell. 2008, 134: 1066-1078 (Featured cover story *equal contribution)




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Lab webpagehttp://www.synyeast.org