Yanmei LI

Tsinghua University

Department of Chemistry

Professor

Education:

1982.9-1987.7   B.Sc.,  Department of Chemistry, TsinghuaUniversity

1987.9-1989.12  M.S.,   Department of Chemistry, TsinghuaUniversity

1989.12-1992.7  Ph.D.,  Department of Chemistry, TsinghuaUniversity

Experience

1992.7-1993.12  Department of Chemistry, TsinghuaUniversity Lecturer

1993.12-1998.8  Department of Chemistry, TsinghuaUniversity Associate Professor

1996.10-1997.10  Institute of Organic Chemistry, University of Karlsruhe, Germany Postdoctor

1998.8-present   Department of Chemistry, TsinghuaUniversity Professor 

Expertise and Research Interests

Her research interests are focused on the synthesis of peptides and peptide-conjugates that have bioactivities, the studies related to posttranslational modification of proteins. Recent research interest also focus on the self-assembly of peptides and peptide-conjugates, inhibitors targeting the abnormal peptide aggregates. Recently, her group is also working in the development of glycopeptides vaccines for tumor therapy. As the principal investigator, she has published more than 100 peer-reviewed papers.

Selected Publication

Huang ZH, Shi L, Ma JW, Sun ZY, Cai H, Chen YX, Zhao YF, Li YM. A totally synthetic, self-assembling, adjuvant-free, MUC1 glycopeptide vaccine for cancer therapy. J. Am. Chem. Soc. 2012, 134: 8730-8734.

Cai H, Sun ZY, Chen MS, Zhao YF, Kunz H, Li YM. Synthetic Multivalent Glycopeptide-Lipopeptide Antitumor Vaccines: Impact of the Cluster Effect on the Killing of Tumor Cells. Angew. Chem. Int. Ed. 2014, 53:1699-1703.

Contact

Department of Chemistry,Tsinghua University 

phone：+86-10-62794258

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