刘铮 

清华大学   化学工程系

教育部长江学者特评教授

博士生导师

教育经历

1987年         获清华大学化学工程系学士学位

1989年         获清华大学化学工程系硕士学位

1993年         获清华大学化学工程系博士学位

1993-1994年    获联合国教科文组织资助在日本东京工业大学生命理工部进修

 研究方向

研究方向为化学与生物分子工程，内容包括蛋白质构象调控及其在生物反应和分离过程中的应用、纳米酶制剂技术及其在工业生物催化中、土壤生物修复技术及其应用等。发表刊物论文180余篇，其中SCI收录110余篇，译著2部，国际学术专著章节3章，授权发明专利12项。培养全国优秀百篇博士论文1名。

担任职务

教育部科学技术委员会化学化工学部委员会委员

中国化工学会生物化工专业委员会副主任

《Chinese Journal of Chemical Engineering》、《过程工程学报》、《化学通报》编委。

所获荣誉

教育部长江学者奖励计划特聘教授

代表论文

Lyu FJ, Zhang YF, Zare RN, Ge J^*, and Liu Z^*. One-Pot Synthesis of Protein-Embedded Metal−Organic Frameworks with Enhanced Biological Activities. Nano Letters. 2014, 14: 5761-5765.

Zhang YF, Lyu FJ, Ge J^* and Liu Z^*. Ink-jet printing an optimal multi-enzyme system. Chem Commun. 2014, 50: 12919-12922.

Li ZX, Zhang YF, Su YC, Ouyang PK, Ge J^* and Liu Z^*. Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes. Chem Commun. 2014, 50: 12465-12468.

Kong X, Qi SS, Lu DN* and Liu Z^*. Surface tension effects on the phase transition of a DPPC bilayer with and without protein: a molecular dynamics simulation. Physical Chemistry Chemical Physics. 2014, 16: 8434-8440.

Kong X, Li ZX, Lu DN^*, Liu Z^* and Wu JZ. Multiscale simulation of surfactant–aquaporin complex formation and water permeability. RSC Advances. 2014, 4:37592–37599.

联系方式

清华大学化学工程系

北京100084，中国

电话：+86-10-62779876

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

刘磊 

清华大学   化学系

教授，博士生导师

教育经历

1999年         获中国科学技术大学学士学位

2004年        获Columbia University博士学位

2004 – 2007年 Scripps Research Institute博士后研究

2007-至今     清华大学任教

研究方向

1. 蛋白质的化学合成与生物医学应用
2. 金属簇催化剂与有机分子催化转化

担任职务

国际学术期刊《Organic Biomolecular Chemistry》副主编

代表论文

Zheng JS, Yu M, Qi YK, Tang S, Shen F, Wang ZP, Xiao L, Zhang L, Tian CL*; Liu L*. J. Am. Chem. Soc. 2014, 136: 3695-3704.

Zheng JS, Tang S, Qi YK, Wang ZP, Liu L*. Nature Protocols. 2013, 8:2483-2495

联系方式

清华大学化学系

北京100084，中国

电话：+86-10-62780027

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

刘德华 

清华大学   化学工程系/应用化学所

教授，博士生导师

教育经历

 研究方向

主要研究领域包括可再生资源利用、生物能源工程、发酵工程与技术、生物反应器等。在这些领域，迄今已发表论文190余篇，其中SCI收录100多篇；申请专利57项，其中已有49项获得授权。主持并参与了多项国家攻关、“863”、“973”、“国家重点工业性试验”、“国家高新技术产业化示范工程”、“对发展中国家科技援助”项目等多个纵向项目；并与国内外的多个企业合作进行项目研究。同时，与欧洲、美国、巴西、日本的众多国际同行专家进行了广泛的交流合作。2010年，与巴西里约热内卢联邦大学合作成立“清华大学中国-巴西气候变化与能源技术创新研究中心”，并开展了丰富多彩的活动和多项项目合作。

担任职务

国际生物能源会议，主席，已办7届

《Biofuels》，《International Journal of Industrial Biotechnology》，《生物工程学报》，《过程工程学报》，《高校化工学报》《生物产业技术》编委。

所获荣誉

2011年，生物工程学报优秀特邀编辑奖，《生物工程学报》
2010年，全国化工优秀科技工作者，中国石油和化学工业协会
2010年，清华大学先进工作者，清华大学
2007年，生物柴油和1,3-丙二醇耦合生产关键技术及产业化示范，第三届中国技术市场协会金桥奖，教育部科技发展中心
2006年，生物法耦合生产生物柴油和1，3－丙二醇的应用基础研究，中国石油和化学工业协会科技进步一等奖
2003年，学术新人奖，清华大学
2002年，清华大学先进工作者，清华大学

联系方式

清华大学化学工程系

北京100084，中国

电话：+86-10-62792128

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

李艳梅 

清华大学   化学系

教授，博士生导师

教育经历

1987年         获清华大学化学系学士学位

1989年         获清华大学化学系硕士学位

1992年         获清华大学化学系博士学位

1992.7-1993.12   清华大学化学系讲师

1993.12-1998.8   清华大学化学系副教授

1996.10-1997.10  德国卡尔斯大学有机化学所博士后

1999.4至今      清华大学化学系博导

 研究方向

长期从事“生物有机化学与化学生物学”的研究。研究重点是翻译后修饰多肽和蛋白质的合成，翻译后修饰对多肽和蛋白质结构与功能的影响，多肽、蛋白质非正常聚集的影响因素，并在此基础上探讨针对相关重大疾病治疗的新型活性分子的设计、合成与评价。作为通讯联系人，近年来在Angew. Chem. Int. Ed., J. Am. Chem. Soc., J. Bio. Chem., Chem. Biol.等国际学术刊物上发表科研论文一百余篇。教材1本，译著3本。在国内、国际学术会议上做邀请报告和主旨报告30余次。

担任职务

科技部国家重大科学研究计划项目（973项目）首席科学家。

现任生命有机磷化学及化学生物学教育部重点实验室主任。

现任以下国际国内学术期刊Organic Letters, Frontiers in Chemical Biology, Journal of Peptide Science, International Journal of Peptide Research and Therapeutics, Acta Biochimica et Biophysica Sinica编委。

所获荣誉

研究成果曾获教育部自然科学二等奖、教育部科技进步二等奖。 获茅以升北京青年科技奖提名奖。

代表论文

Huang ZH, Shi L, Ma JW, Sun ZY, Cai H, Chen YX, Zhao YF, Li YM. A totally synthetic, self-assembling, adjuvant-free, MUC1 glycopeptide vaccine for cancer therapy. J. Am. Chem. Soc. 2012, 134: 8730-8734.

Cai H, Sun ZY, Chen MS, Zhao YF, Kunz H, Li YM. Synthetic Multivalent Glycopeptide-Lipopeptide Antitumor Vaccines: Impact of the Cluster Effect on the Killing of Tumor Cells. Angew. Chem. Int. Ed. 2014, 53:1699-1703.

联系方式

清华大学化学系

北京100084，中国

电话：+86-10-62794258

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

李梢

清华大学   自动化系/清华信息国家实验室

教授，博士生导师

教育经历

1995年            获北京中医药大学医学学士学位

1998年            获皖南医学院医学硕士学位

2001年            获北京中医药大学医学博士学位

2001.9－2009.11    清华大学 博士后、讲师、副研究员

2009至今           清华大学 教授

研究方向

网络药理学、生物信息学与中医药现代化，致力于建立网络药理学理论与方法，并用于炎症

和肿瘤等疾病、中医药的研究。

担任职务

清华信息国家实验室 生物信息学研究部副主任

清华信息科学与技术国家实验室 中医药交叉研究中心主任

世界中医药学会联合会 网络药理学专业委员会 会长

中国药理学会 网络药理学专业委员会 副主任委员

中国研究型医院学会 生物标志物专业委员会 副主任委员

所获荣誉

国家杰出青年科学基金、国家“万人计划”科技创新领军人才、科技部中青年科技创新领军人

才、教育部新世纪优秀人才，曾获国家科技进步二等奖、国家教学成果二等奖、全国优秀博

士学位论文等奖励。

代表论文

1. Zhang P, Yang M, Zhang Y, Xiao S, Lai X, Tan A, Du S, Li S*. Dissecting the single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancer. Cell Reports 2019; 27:1934-1947

2. Guo Y, Bao C, Ma D, Cao Y, Li Y, Xie Z*, Li S*. Network-based combinatorial CRISPR-Cas9 screens identify synergistic modules in human cells. ACS Synthetic Biology 2019;8:482−490 (Cover)

3. Guo Y, Nie Q, MacLean A, Li Y, Lei J*, Li S*. Multiscale modeling of inflammation-induced tumorigenesis reveals competing oncogenic and oncoprotective roles for inflammation. Cancer Research 2017;77(22):6429-6441

4. Zu S, Chen T, Li S*. Global optimization-based inference of chemogenomic features from drug-target interactions. Bioinformatics 2015;31(15):2523-2529

5. Liang X, Li H, Li S*. A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-wei-di-huang Pill as a case study. Molecular BioSystems 2014,10(5):1014-1022 (Cover)

6. Zhao S, Li S*. A co-module approach for elucidating drug-disease associations and revealing their molecular basis. Bioinformatics 2012;28(7):955-961

7. Li S*, Zhang B, Zhang NB. Network target for screening synergistic drug combinations with application to traditional Chinese medicine. BMC Systems Biology 2011;5(S1):S10

8. Wu X, Jiang R, Zhang MQ, Li S*. Network-based global inference of human disease genes. Molecular Systems Biology 2008;4:189

9. Li S*, Zhang Z, Wu L, Zhang X, Li Y, Wang Y. Understanding ZHENG in traditional Chinese medicine in the context of neuro-endocrine-immune network. IET Systems Biology 2007;1(1):51-60

10. Li S*, Wu LJ, Zhang ZQ. Constructing biological networks through combined literature mining and microarray analysis: a LMMA approach. Bioinformatics 2006;22:2143-2150

联系方式

清华大学自动化系

北京100084，中国

电话：+86-10-62797035

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

个人主页：http://bioinfo.au.tsinghua.edu.cn/member/lishao/

董家鸿

清华大学   长庚医院

教授，博士生导师

教育经历

1982年       获徐州医学院学士学位

1993年       获第三军医大学博士学位

1993年       第三军医大学将西南医院肝胆外科工作

1994年       晋升为副主任医师，获得硕士研究生导师资格

1996年       晋升为主任医师，获博士生导师资格

2006年       调入解放军总医院肝胆外科

2007年12月  晋升为专业技术三级

2013年       晋升为专业技术二级

2014年       起担任北京清华长庚医院执行院长、学术委员会主席

研究方向

肝胆外科手术治疗和相关基础研究，肝脏移植

担任职务

北京清华长庚医院执行院长

美国外科学会荣誉会士、欧洲外科协会荣誉会士、法国国家外科科学院外籍荣誉院士、美国外科学院院士、国际消化外科学会执行委员会委员、中华外科学会常委、中华器官移植学会常委、国家卫生部人体器官移植应用委员会委员、中华医学会胆道外科学组主任委员、全军肝胆外科专业委员会主任委员、中央保健委员会会诊专家、《中华消化外科杂志》总编辑。

所获荣誉

获国家科技进步一等奖、重庆科技进步一等奖、军队医疗成果一等奖、军队科技进步一等奖各1项，军队医疗成果二等奖2项，国家发明专利2项。

代表论文

Lai YH, Duan WD, Yu Q, Ye S, Xiao NJ, Zhang DX, Huang ZQ, Yang ZY and Dong JH. Outcomes of liver transplantation for end-stage biliary disease: A comparative study with end-stage liver disease. World J Gastroenterol. 2015, 21:6296-303.

Dong JH, Ye S, Duan WD, Ji WB and Liang YR. Feasibility of liver graft procurement with donor gallbladder preservation in living donor liver transplantation. Hepatol Int. 2015 May 15 [Epub ahead of print].

Huang X, Liang B, Zhao XQ, Zhang FB, Wang XT and Dong JH. The effects of different preoperative biliary drainage methods on complications following pancreaticoduodenectomy. Medicine. 2015, 94:e723.

Li HL, Ji WB, Zhao R, Duan WD, Chen YW, Wang XQ, Yu Q, Luo Y and Dong JH. Poor prognosis for hepatocellular carcinoma with transarterial chemoembolization pre-transplantation: retrospective analysis. World J Gastroenterol. 2015, 21:3599-606.

联系方式

清华大学长庚医院

北京100084，中国

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

邓海腾

清华大学 生命科学学院

教授，博士生导师

教育经历

1985年        获武汉大学大学学士学位

1996年        获宾州州立大学大学（Pennsylvania State University）博士学位

1996-1999年   加拿大阿尔伯达(Alberta)大学和美国橡树岭国家实验室（Oak Ridge National Lab）做博士后研究

2000.1-2001.12  讲师, 发育生物学系, 爱因斯坦医学院

2001.12-2003.7  助理教授, 医学系, 爱因斯坦医学院

2003.8-2003.12  助理教授, 内布拉斯加大学

2004.1-2009.7   研究助理教授, 洛克菲勒大学

2009.9-2011.2   研究副教授和蛋白质组中心主任,洛克菲勒大学

2008.9至今    客座研究员, 纽约大学

2011.3至今    客座教授, 洛克菲勒大学

2011.3至今    清华大学教授

研究方向

构建调控肿瘤发生和发展的蛋白质稳态调控网络；鉴定新的衰老相关的生物标志物和肿瘤标志物；研究肿瘤抗药机制；发现延缓和逆转衰老的新方法和靶点。

代表论文

Feng S, Zhang L, Adilijiang G, Liu GY, Deng HT. Substrate Profiling of Glutathione S-transferase with Engineered Enzymes and Matched Glutathione Analogues. Angew Chem Int Ed Engl. 2014, 53:7149-53.

Jin LX, Zheng ZG, Jiang XY, Huo Y, Deng HY, Chen YL, Lian QQ, Ge RS, Deng HT. Down-regulation of Rab 5C-dependent Endocytosis and Glycolysis in Cisplatin-resistant Ovarian Cancer Cell Lines. Molecular and Cellular Proteomics. 2014, 13:3138-51.

Hu YD, Wang HL, Xu RH, Wang QT, Deng HT. NAD-Mediated Protein Expression, Cell Proliferation, and Responses to Oxidative Stress. Journal of Proteome Research. 2014 ,13:786-95.

Zhang NW, Malamad D, Deng HT. Quantitative Analysis of Differentially Expressed Salivary Proteins in HIV-1 Seropositive Individuals. Analytica Chimica Acta. 2013, 774:61-6. 

联系方式

清华大学生命科学学院

北京100084，中国

电话：+86-010-62789415

Email: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。

Kang, T., White, J. T., Xie, Z., Benenson, Y., Sontag, E., & Bleris, L. (2013). Reverse Engineering Validation using a Benchmark Synthetic Gene Circuit in Human Cells. ACS Synthetic Biology. doi:10.1021/sb300093y

Kashyap, N., Pham, B., Xie, Z., & Bleris, L. (2013). Transcripts for combined synthetic microRNA and gene delivery. Molecular bioSystems. doi:10.1039/c3mb70043g

Guo W, Chung, W-Y, Qian, M, Pellegrini, M, Zhang, MQ (2013). Characterizing the strand-specific distribution of non-CpG methylation in human pluripotent cells. NAR. In press.

Guo W, Fiziev P, Yan W, Cokus S, Sun X, Zhang MQ, Chen PY, Pellegrini M (2013) BS-Seeker2: a versatile aligning pipeline for bisulfite sequencing data. BMC Genomics. 2013 Nov 10;14(1):774.

Jiang R, Zhang X, Zhang MQ (2013) Basics of Bioinformatics: Lecture Notes of Graduate Summer School on Bioinformatics of China. Book, ISBN-10:3642389503, ISBN-13: 978-3642389504. Springer 2013 edition.

Chen Y, Ding Y, Yang L, Yu J, Liu G, Wang X, Zhang S, Yu D, Song L, Zhang H, Zhang C, Huo L, Huo C, Wang Y, Du Y, Zhang H, Zhang P, Na H, Xu S, Zhu Y, Xie Z, He T, Zhang Y, Wang G, Fan Z, Yang F, Liu H, Wang X, Zhang X, Zhang MQ, Li Y, Steinbüchel A, Fujimoto T, Cichello S, Yu J, Liu P. (2013) Integrated omics study delineates the dynamics of lipid droplets in Rhodococcus opacus PD630. NAR, [Epub ahead of print], PMID:24150943.

Tam KW, Zhang W, Soh J, Stastny V, Chen M, Sun H, Thu K, Rios JJ, Yang C, Marconett CN, Selamat SA, Laird-Offringa IA, Taguchi A, Hanash S, Shames D, Ma X, Zhang MQ, Lam WL, Gazdar A (2013) CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non-Small-Cell Lung Cancer. J Thorac Oncol. 8:1378-88. PMID:24077454.

Wu D, Gu J, Zhang MQ. (2013) FastDMA: An Infinium HumanMethylation450 Beadchip Analyzer. PLoS One. 2013 Sep 5;8(9):e74275. PMID:24040221.

Kim MV, Ouyang W, Liao W, Zhang MQ, Li MO. (2013) The transcription factor Foxo1 controls central-memory CD8+ T cell responses to infection. Immunity. 39:286-97. PMID:23924514.

Qin J, Li MJ, Wang P, Wong NS, Wong MP, Xia Z, Tsao GS, Zhang MQ, Wang J (2013) ProteoMirExpress: inferring microRNA-centered regulatory networks from high throughput proteomic and mRNA expression data. Mol. Cell. Proteomics, [PubMed – in process] PMID:23924514.

Zhou D, Wu D, Li Z, Qian M, Zhang MQ (2013) Population dynamics of cancer cells with cell-state conversions. Quant. Biol. 2:2095-4689. DOI: 10.1007/s40484-013-0014-2.

Xie W, Schultz M, Lister R, Hou Z, Rajagopal N, Ray P, Whitaker JW, Tiam S, Hawkins DR, Leung D, Yang H, Wang T, Swanson SA, Zhang J, Zhu Y, Lee AY, Kim A, Nery J, Urich MA, Kuan S, Yen C, Klugman S, Yu P, Suknuntha K, Propson NE, Chen H, Edsall LE, Wagner U, Li Y, Ye Z, Kulkarni A, Xuan Z, Chung W, Chi NC, Antosiewicz-Bourget J, Slukvin I, Stewart R, Zhang MQ, Wang W, Thomson JA, Eckert JR, Ren B (2013) Epigenomic Analysis of Multi-lineage Differentiation of Human Embryonic Stem Cells. Cell, 153:1134-48. PMID:23664764.

Wen-Yu Chung, Robert J. Schmitz, Tanya Biorac, Delia Ye, Miroslav Dudas, Gavin D. Meredith, Christopher C. Adams, Joseph R. Ecker and Michael Q. Zhang (2013) Constructing hepitypes: phasing local genotype and DNA methylation. JNSNE, In press.

May P, Liao W, Wu Y, Shuai B, McCombie WR, Zhang MQ, Liu QA (2013) The Effects of Carbon Dioxide and Temperature on microRNA Expressions in Arabidopsis Development. Nat. Comm. 4:2145. PMID:23900278.
Ma X, Wang YW, Zhang MQ, Gazdar AF (2013) DNA methylation data analysis and its application to cancer research. Epigenomics. 5:301-16. PMID:23750645.

Wu J, Anczuków O, Krainer AR, Zhang MQ*, Zhang C* (2013) OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds. Nucl. Acid. Res. 41:5149-5163. PMID:23571760.

Wang C, Zhang MQ, Zhang Z (2013) Computational identification of active enhancers in model organisms. Genomics, Proteomics Bioinformatics, pii:S1672-0229(13)00047-8. PMID:23685394.

Megha Rajaram; Jianping Zhang; Tim Wang; Cem Kuscu; Mamoru Kato; Vladimir Grubor; Robert Weil; Asluag Helland; Anne-Lise Borrenson-Dale; Kathleen Cho; Douglas A Levine; Alan N Houghton; Jedd D Wolchok; Lois Myeroff; Sanford D Markowitz; Michael Zhang; Alex Krasnitz; Robert Lucito; David Mu; Scott Powers (2013) Two Distinct Categories of Focal Deletions in Cancer Genomes. PLoS ONE, 8:e66264. PMID:23805207.

Jin Gu, Zhenyu Xuan. Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures. PLoS ONE 2013, 8(11):e81032.

Dingming Wu, Jin Gu, Michael Zhang. FastDMA: An Infinium HumanMethylation450 Beadchip Analyzer. PLoS ONE 2013, 8(9):e74275.

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Jin Gu, Zhenyu Xuan. Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures. PLoS ONE 2013, 8(11):e81032.

Dingming Wu, Jin Gu, Michael Zhang. FastDMA: An Infinium HumanMethylation450 Beadchip Analyzer. PLoS ONE 2013, 8(9):e74275.

Ting Wang, Jin Gu, Jun Yuan, Ran Tao, Yanda Li, Shao Li. Inferring pathway crosstalk networks using gene set co-expression signatures. Molecular BioSystems 2013, 9(7):1822-1888.

Rui Li, Tao Ma, Jin Gu, Xujun Liang, Shao Li. Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients. Scientific Reports 2013, 3:1543.

Feng Zeng, Rui Jiang, Ting Chen, PyroHMMsnp: a SNP caller for Ion Torrent and 454 sequencing data, Nucleic Acids Research, accepted, 2013.

Li R, Ma T, Gu J, Liang X, Li S. Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients. Scientific Reports 2013;3:1543.

Zhang B, Wang X, Li S. An integrative platform of TCM network pharmacology and its application on an herbal formula, Qing-Luo-Yin. Evidence-based.

Zhang B, Liu L, Zhao S, Wang X, Liu L, Li S. Vitexicarpin acts as a novel angiogenesis inhibitor and its target network. Evidence-based Complementary and Alternative Medicine 2013:278405.

Freeberg MA, Han T,Moresco JJ, Kong A, Yang YC2, Lu ZJ2, Yates JR, Kim JK. (2013) Pervasive and dynamic protein binding sites of the mRNA transcriptome in Saccharomyces cerevisiae. Genome Biology.

Kudron M, Niu W, Lu Z, Wang G, Gerstein M, Snyder M, Reinke V. (2013) Tissue-specific direct targets of Caenorhabditis elegans Rb/E2F dictate distinct somatic and germline programs. Genome Biology.

Matthew H Larson, Luke A Gilbert, Xiaowo Wang, Wendell A Lim, Jonathan S Weissman & Lei S Qi, CRISPR interference (CRISPRi) for sequence-specific control of gene expression, Nature Protocols, 2013; 8, 2180–2196.