YING TAN

 

YING TAN

Assistant Professor

Tsinghua Shenzhen International Graduated School

 

  

Education

2005-2010, Ph.D. in chemical biology, Central China Normal University

2001-2005, B.S. in applied chemistry, Central China Normal University

Professional Experience

Oct 2012-present, Lecturer and Associate Professor, Graduate School at Shenzhen,Tsinghua University

Oct 2016-Oct 2017, Visiting Scholar, National University of Singapore

Jul 2010-Jul 2012, Postdoctoral Fellow, Guangdong Provincial Key Laboratory of Chemical Biology, Graduate School at Shenzhen, Tsinghua University

 

Research Interest

l  Drug development systems based on synthetic biology, cellular phenotypes and biological orthogonality.

l  Non-invasive, highly sensitive, and highly specific disease diagnostic systems and devices.

l  Novel artificial intelligence algorithms developed and applied to multi-omics research, disease diagnosis, and drug design.

 

Awards

2021 Excellent Teacher of Shenzhen； 

Third prize in the 9th Tsinghua University Young Teachers Teaching Competition； 

Excellent Master thesis advisor of Tsinghua University

 

Selected Publications

  1. Zheng-Xin Zhou, Yue-Liu-Ting Fu, Chen Zhang, Yuan-Heng Li, Bin-Jun Zhang, Yu-Qing Xiao, Yu-Jie Li, Li-Yan Chen, Li Rao,* Ying Tan,* Wen-Jing Xiao, and Liang-Qiu Lu*. Modular Synthesis of Planar-Chiral Cyclononenes via trans-Retentive Trapping of π‑Allyl-Pd Dipoles. Journal of the American Chemical Society, 2025, 147, 3223−3232.
  2. Yu-Qing Xiao, Kai-Xin Fang, Zhihan Zhang, Chen Zhang, Yu-Jie Li, Bao-Cheng Wang, Bin-Jun Zhang, Yu-Qing Jiang, Miao Zhang, Ying Tan*, Wen-Jing Xiao and Liang-Qiu Lu*, Hyperconjugation-Driven Isodesmic Reaction of Indoles and Anilines: Reaction Discovery, Mechanism Study, and Antitumor Application. Angewandte Chemie International Edition. 2024, e202408426.
  3. Chen Zhang, Junqiao Wang, Hui Chen, Muzi Ouyang, Yuanheng Li, Chunyan Tan, Yuyang Jiang, and Ying Tan*. A Therapeutic Pretargeting Strategy for Triple-Negative Breast Cancer Based on a Bioorthogonal Reaction and a Self-Assembled Peptide. Advanced Functional Materials, 2024, 2313090.
  4. Xiaoqi Xue, Chen Zhang, Xiaolin Li, Junqiao Wang, Haowei Zhang, Ying Feng, Naihan Xu, Hongyan Li, Chunyan Tan, Yuyang Jiang, Ying Tan*. mRNA PROTACs: engineering PROTACs for high-efficiency targeted protein degradation. MedComm. 2024, 5:e478.
  5. Hui Chen, Ying Feng, Feng Liu, Chunyan Tan, Naihan Xu, Yuyang Jiang,** Ying Tan*. Universal smartphone-assisted label-free CRISPR/Cas12a-DNAzyme chemiluminescence biosensing platform for on-site detection of nucleic acid and non-nucleic acid targets. Biosensors and Bioelectronics, 2024, 247, 115929.
  6. Bao-Cheng Wang, Li Rao, Kai-Xin Fang, Bao-Le Qu, Fen-Ya Xiong, Ying Feng, Ying Tan,* Liang-Qiu Lu,* and Wen-Jing Xiao. Dearomatization-Rearomatization Reaction of Metal-Polarized Aza-ortho-Quinone Methides. Angewandte Chemie International Edition. 2023, e202301592.
  7. Dongyang Li, Tianruo Shen, Xiaoqi Xue, Weijie Chen, Wenjun Tao, Weijie Chi, Sheng Hua Liu, Ying Tan*, Xiaogang Liu*, Jun Yin*. Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy. Science China Chemistry, 2023, 66: 2329-2338.
  8. Chen Li, Hui Chen, Tingting Fan, Jingru Zhao, Zheng Ding, Zeyu Lin, Shuqing Sun, Chunyan Tan, Feng Liu, Hongtao Jian*, Ying Tan*. A visualized automatic particle counting strategy for single-cell level telomerase activity quantification. VIEW, 2023, 20220078.
  9. Bao-Cheng Wang, Tingting Fan, Fen-Ya Xiong, Peng Chen, Kai-Xin Fang, Ying Tan,* Liang-Qiu Lu,* and Wen-Jing Xiao De Novo Construction of Chiral Aminoindolines by Cu-Catalyzed Asymmetric Cyclization and Subsequent Discovery of an Unexpected Sulfonyl Migration. Journal of the American Chemical Society, 2022, 144, 19932-19941.
  10. Junyue Chen, Gerile Oudeng, Hongtao Feng, Sixi Liu, Hung-Wing Li, Yi-Ping Ho, Yan Chen,* Ying Tan,* and Mo Yang*. 2D MOF Nanosensor-Integrated Digital Droplet Microfluidic Flow Cytometry for In Situ Detection of Multiple miRNAs in Single CTC Cells. Small, 2022, 2201779.

 

Contact Information

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