Working Experience:
02/2022 – present Assistant Professor, Tsinghua University
10/2018 – 10/2021 Postdoctoral Research Fellow, The University of Hong Kong
03/2018 – 9/2018 Research Assistant,The University of Hong Kong
Education :
01/2014 – 06/2018 : Doctor of Philosophy (Bioinorganic Chemistry), The University of Hong Kong,
Supervisor: Prof. SUN, Hongzhe
Co-supervisor: Dr. Richard KAO, Yi-Tsun
Research Interest：
His research focuses on interdisciplinary studies in metallochemical biology, synthetic biology, synthetic chemistry, and computational biology. Centered on the multi-scale exploration of biological resources and the metallization activity modification of biomolecules, he designs innovative cross-species metalloprotein/peptide element libraries, develops data-driven platforms for metalloprotein/peptide design and directed evolution, and customizes functionalized metal-based drugs and chronic disease prevention products for anti-infection, anti-tumor, and anti-fibrosis applications.
Royal Society of Chemistry Books Awards at ASBIC8, 2016
Selected Publications:
1. Wang R#, Lai TP#, Gao P#, Zhang H#, Ho PL, Woo PC, Ma G, Kao RYT, Li H, Sun H*. “Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors” Nat. Commum., 2018, 9, 439.
2. Sun H#*, Zhang Q#, Wang R#*(Co-first author and Co-corresponding author), Wang H, Wong YT, Wang M, Hao Q, Yan A, Kao YT, Ho PL, Li H, “Resensitizing superbugs carrying both blaMBL and mcr genes to antibiotics by auranofin” Nat. Commum., 2020, 11, 5263.
3. Yuan S#, Wang R#(Co-first author), Chan FW#, Zhang J, Cheng T, Chik KH, Ye Z-W, Wang S, Jin L, Li H, Jin DY, Yuen KY*, Sun H*, “Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters” Nat. Microbiol, 2020, 5, 1439–1448.
4. Cheng H, Huang S, Cai L., Xu Y, Wang R*, Zhang Y.*., “Focus Your Attention: Multiple Instance Learning with Attention Modification for Whole Slide Pathological Image Classification.” IEEE Transactions on Circuits and Systems for Video Technology. 2025, DOI: 10.1109/TCSVT.2025.3528625.
5. Zhang Q#, Wang R#(Co-first author), Wang M, Liu C, Koohi-Moghadam M, Wang H, Ho P-L, Li H, Sun H*, Proc. Natl. Acad. Sci. U.S.A., 2022, 119, e2119417119.
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