Zhuo Xiong

 

 

Zhuo Xiong

Professor

Department of Mechanical Engineering, Tsinghua University

  

Education and work experience

09/1994-07/1998 B.S., Department of Mechanical Engineering, Tsinghua University, Beijing, China

09/1998-01/2003 M.S.&Ph.D., Department of Mechanical Engineering, Tsinghua University, Beijing, China

03/2001-12/2002, Research Intern, Department of Mechanical Engineering, Tsinghua University, Beijing, China

12/2002-12/2005, Lecturer, Department of Mechanical Engineering, Tsinghua University, Beijing, China

12/2005-06/2010, Associate Professor, Department of Mechanical Engineering, Tsinghua University, Beijing, China

2010,                     Promoted to Professor by Tsinghua University

07/2013-06/2016, Guest Researcher, Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing, China

05/2013-04/2015, Adjunct Professor, Graduate school at Shenzhen, Tsinghua University, Shenzhen, China

03/2013-03/2018, Guest Professor, The Fourth Military Medical University (Air Force Medical University), Xi’an, China

07/2020-06/2023, Tenured Associate Professor, Department of Mechanical Engineering, Tsinghua University, Beijing, China

06/2023-Present,   Professor, Department of Mechanical Engineering, Tsinghua University, Beijing, China

 

Research Interest：

3D Bioprinting

Regenerative Engineering

In Vitro Tumor Model

3D Bioprinting in Space

Digital Information Storage in DNA

Additive Manufacturing

 

Awards:

Science and Technology Award of Chinese Machinery Industry. Additive Manufacturing Technology and Equipment for Biomimetic Multi-scale Tissue Engineering Scaffolds. (2024)

Beijing Science and Technology Award. Three-dimensional diagnosis and treatment of dentofacial deformity and its clinical application. (2006)

 

Selected Publications

  1. Luo, H., Huang, W., He, Z., Fang, Y., Tian, Y., Xiong, Z. Engineered Living Memory Microspheroid-Based ArchivalFile System for Random Accessible In Vivo DNA Storage. Advanced Materials, 2025, 202415358
  2. Zhang, Z., Zhou, X., Fang, Y., Xiong, Z., Zhang, T.AI-driven 3D bioprinting for regenerative medicine: From bench to bedside. Bioactive Materials, 2025, 45, 201–230
  3. Zhou, X., Fang, Y., Zhang, T.,Xiong, Z.Retrospective: Advances and opportunities of 3D Bioprinting in China over Three Decades. Additive Manufacturing Frontiers, 2024, 3(4), 200157
  4. Zhang, Y., Hu, Q., Pei, Y., ... Gu, J., Xiong, Z.A patient-specific lung cancer assembloid model with heterogeneous tumor microenvironments. Nature Communications, 2024, 15(1), 3382
  5. Wu, B., Zeng, Z., Fang, Y., ... Zhang, T., Xiong, Z.Omnidirectional elastic constraint-based embedded 3D printing in non-yield stress fluids for engineering complex tissues. Materials Today, 2024, 80, 74–86
  6. Pei, B., Zhou, Y., Yang, Y., ... Mi, S., Xiong, Z.A Novel DNA-Based Dual-Mode Data Storage System with Interrelated Concise and Detailed Data. Small Science, 2024, 4(11), 2400094
  7. Xu, X., Gao, Y., Dai, J., ... Zhang, Y., Xiong, Z.Gastric Cancer Assembloids Derived from Patient-Derived Xenografts: A Preclinical Model for Therapeutic Drug Screening. Small Methods, 2024, 8(9), 2400204
  8. Mo, X., Zhang, Y., Wang, Z., Zhou, X., Zhang, Z., Fang, Y., Fan, Z., Guo, Y., Zhang, T., Xiong, Z. Satellite-Based On-Orbit Printing of 3D Tumor Models. Advanced Materials, 2024, 35(34), 2309618
  9. Liu, Y., Li, X., Pei, B., Ge, L., Xiong, Z., Zhang, Z. Towards smart scanning probe lithography: a framework accelerating nano-fabrication process with in-situ characterization via machine learning. Microsystems and Nanoengineering. 2023, 9(1), 128
  10. Fang, Y., Ji, M., Wu, B., Xu, X., Wang, G., Zhang, Y., Xia, Y., Li, Z., Zhang, T., Sun, W., Xiong, Z. Engineering Highly Vascularized Bone Tissues by 3D Bioprinting of Granular Prevascularized Spheroids. ACS Applied Materials and Interfaces. 2023, 15(37): 43492–43502
  11. Fang, Y., Ji, M., Yang, Y., Guo, Y., Sun, R., Zhang, T., Sun, W., Xiong, Z. 3D printing of vascularized hepatic tissues with a high cell density and heterogeneous microenvironment. Biofabrication. 2023, 15, 045004
  12. Ye, M., Shan, Y., Lu, B., Luo, H., Li, B., Zhang, Y., Wang, Z., Guo, Y., Ouyang, L., Gu, J.,Xiong, Z., Zhang, T.Creating a semi-opened micro-cavity ovary through sacrificial microspheres as an in vitro model for discovering the potential effect of ovarian toxic agents. Bioactive Materials, 2023, 26: 216–230
  13. Fang, Y., Guo, Y., Wu, B., Liu, Z., Ye, M., Xu, Y., Ji, M., Chen, L., Lu, B., Nie, K., Wang, Z., Luo, J., Zhang, T., Sun, W., Xiong, Z.Expanding Embedded 3D Bioprinting Capability for Engineering Complex Organs with Freeform Vascular Networks. Advanced Materials, 2023, 35(22), 2205082
  14. Fang, Y., Wang, C., Liu, Z., Ko, J., Chen, L., Zhang, T., Xiong, Z., Zhang, L., Sun, W. 3D Printed Conductive Multiscale Nerve Guidance Conduit with Hierarchical Fibers for Peripheral Nerve Regeneration. Advanced Science, 2023, 10(12), 2205744
  15. Lu, B., Ye, M., Xia, J., Zhang, Z., Xiong, Z., Zhang, T.Electrical Stimulation Promotes the Vascularization and Functionalization of an Engineered Biomimetic Human Cardiac Tissue. Advanced Healthcare Materials. 2023, 2300607
  16. Fang, Y., Sun, W., Zhang, T. and Xiong, Z. Recent advances on bioengineering approaches for fabrication of functional engineered cardiac pumps: A review. Biomaterials. 2022, 280: 121298
  17. Zhang, Y., Wang, Z., Hu, Q., Luo, H., Lu, B., Gao, Y., Qiao, Z., Zhou, Y., Fang, Y., Gu, J., Zhang, T. and Xiong, Z.3D Bioprinted GelMA-Nanoclay Hydrogels Induce Colorectal Cancer Stem Cells Through Activating Wnt/β-Catenin Signaling. Small. 2022, 18(18): 2200364
  18. Fang, Y., Guo, Y., Ji, M., Li, B., Guo, Y., Zhu, J., Zhang, T., and Xiong, Z. 3D Printing of Cell-laden Microgel-based Biphasic Bioink with Heterogeneous Microenvironment for Biomedical Applications. Advanced Funtional Materials. 2021,31(51):2109810

 

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