Center for synthetic and systematic biology of Tsinghua University is composed of a group of researchers from School of Life Sciences，School of Medicines，National Laboratory for Information Science and Technology，Department of Chemical Engineering，Department of Chemistry，Beijing Tsinghua Chang-Geng hospital topromote the inter-disciplinary collaboration in the field of synthetic and systems biology and to expand the domestic and international impact of Tsinghua University in the field. Many key members are joint faculty in School of Information Science and Technology, School of Medicines and School of Life Sciences.

PIs in CSSB include Academician of Chinese Academy of Sciences（1), Thousand Talent Program（1）, 973 Project Chief Scientists（4）, China National Funds for Distinguished Young Scientists and The Cheung Kong Scholars Program（8）, Thousand Youth Talents Program（8）, the Excellent Young Scholars（1）and The National 100 excellent Doctoral Dissertation（1）, including two winners of the ten 973 projects in synthetic biology and the only bioinformatics 973 projects. The research areas cover the high-throughput genomics, regulatory network of complex disease, mechanisms of epi-genomics and genetics, chemical biosynthesis and metabolic engineering, genetic networks and their medical applications, gene synthesis and genome assembly, environmental microbiology, metagenomics and other related fields.

In recent five years, the team has already published more than 120 research articles in high-impact journals including Science, Nature, PNAS, Chemical Reviews, Cancer Cell, Angew. Chem. Int. Ed., Biotechnology Advances, Current Opinions of high-level Biotechnology, Metabolic Engineering magazine etc. The team won the first Prizes of The State Scientific and Technological Progress Award and a second place of The National Award for Technological Invention and became one of the best synthetic biology research team in China by taking advantages of combining the synthesis biology and systems biology.