齐天从

 

 

齐天从

副教授，博士生导师

清华大学，生命科学学院

 

 

研究经历

2003 – 2007     中国农业大学, 学士

2007 – 2012     清华大学, 博士

2012 – 2016     清华大学, 博士后

2016 – 2019     美国加州大学伯克利分校, 唐氏杰出学者, 博士后

2019 – 2022     清华大学生命科学学院, 助理教授

2023-至今        清华大学生命科学学院, 副教授

 

研究方向

植物病虫害影响植物产量与品质，造成严重农业经济损失。实验室研究聚焦于植物与病原微生物互作的分子机理。我们综合运用细胞生物学、生物信息学与结构生物学等多学科手段，旨在解析植物的免疫信号通路与病原菌的致病机制。在此基础上，我们利用合成生物学等技术，进行抗病植物的理性设计与智能改造，为应对重大病虫害、推动作物育种与生产提供理论与技术支撑。

 

代表论文

  1. Wang H, Song S, Gao S, Yu Q, Zhang H, Cui X, Fan J, Xin X, Liu Y, Staskawicz B, Qi T*. The NLR immune receptor ADR1 and lipase-like proteins EDS1 and PAD4 mediate stomatal immunity in Nicotiana benthamiana and Arabidopsis. Plant Cell. 2024, 36(2):427-446. 
  2. Xiao Y, Sun G, Yu Q, Gao T, Zhu Q, Wang R, Huang S, Han Z, Cervone F, Yin H, Qi T, Wang Y, Chai J. A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity. Science. 2024, 383(6684):732-739.
  3. Song S*, Liu B, Song J, Pang S, Song T, Gao S, Zhang Y, Huang H, Qi T*. A molecular framework for signaling crosstalk between jasmonate and ethylene in anthocyanin biosynthesis, trichome development, and defenses against insect herbivores in Arabidopsis. J Integr Plant Biol. 2022,64(9):1770-1788.
  4. Liu B, Seong K, Pang S, Song J, Gao H, Wang C, Zhai J, Zhang Y, Gao S, Li X, Qi T*, Song S*. Functional specificity, diversity and redundancy of Arabidopsis JAZ family repressors in jasmonate and COI1-regulated growth, development and defense. New Phytologist, 2021, 231(4):1525-1545. 
  5. Song S*, Liu B, Zhai J, Zhang Y, Wang K, Qi T*. The intragenic suppressor mutation Leu59Phe compensates for the effect of detrimental mutations in the jasmonate receptor COI1. Plant Journal, 2021, 108(3):690-704. 
  6. Martin R#, Qi T#, Zhang H, Liu F, King M, Toth C, Nogales E, Staskawicz BJ. Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ. Science, 2020, 370(6521):eabd9993.
  7. Horsefield S, Burdett H, Zhang X, Manik MK, Shi Y, Chen J, Qi T, Gilley J, Lai JS, Rank MX, Casey LW, Gu W, Ericsson DJ, Foley G, Hughes RO, Bosanac T, von Itzstein M, Rathjen JP, Nanson JD, Boden M, Dry IB, Williams SJ, Staskawicz BJ, Coleman MP, Ve T, Dodds PN, Kobe B. NAD+ cleavage activity by animal and plant TIR domains in cell death pathways.Science. 2019, 365(6455):793-799.
  8. Qi T, Seong K, ThomazellaD, Kim JR, Pham J, Seo E, Cho MJ, Schultink A and Staskawicz B. NRG1 functions downstream of EDS1 to regulate TIR-NLR-mediated plant immunity in Nicotiana benthamiana. PNAS, 2018, 115(46): E10979–
  9. Wu D#, Qi T#, Li WX, Tian H, Gao H, Wang J, Ge J, Yao R, Ren C, Wang XB, Liu Y, Kang L, Ding SW, Xie D. Viral effector protein manipulates host hormone signaling to attract insect vectors. Cell Research, 2017, 27(3): 402–
  10. Qi T, Huang H, Song S, Xie D. Regulation of jasmonate-mediated stamen development and seed production by a bHLH-MYB complex in Arabidopsis. Plant Cell, 2015,27(6): 1620–1633.
  11. Qi T, Wang J, Huang H, Liu B, Gao H, Liu Y, Song S, Xie D. Regulation of jasmonate-induced leaf senescence by antagonism between bHLH subgroup IIIe and IIId factors in Arabidopsis. Plant Cell, 2015, 27(6): 1634–1649.
  12. Qi T, Huang H, Wu D, Yan J, Qi Y, Song S, Xie D. Arabidopsis DELLA and JAZ proteins bind the WD-repeat/bHLH/MYB complex to modulate gibberellin and jasmonate signaling synergy. Plant Cell, 2014, 26(3): 1118–
  13. Song S, Huang H, Gao H, Wang J, Wu D, Liu X, Yang S, Zhai Q, Li C, Qi T#, Xie D#. Interaction between MYC2 and ETHYLENE INSENSITIVE3 modulates antagonism between jasmonate and ethylene signaling in Arabidopsis. Plant Cell, 2014, 26(1): 263–
  14. Song S#, Qi T#, Fan M, Zhang X, Huang H, Gao H, Wu D, Guo H, Xie D. The bHLH subgroup IIId factors negatively regulate jasmonate-mediated plant defense and development. PLoS Genetics, 2013, 9(7): e1003653.
  15. Qi T, Song S, Ren Q, Wu D, Huang H, Chen Y, Fan M, Peng W, Ren C, Xie D. The Jasmonate-ZIM-domain proteins interact with the WD-repeat/bHLH/MYB complexes to regulate jasmonate-mediated anthocyanin accumulation and trichome initiation in Arabidopsis thaliana. Plant Cell, 2011, 23(5): 1795–

#:Co-first author; *: Corresponding authors

 

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