马少华
清华大学 清华大学深圳国际研究生院
长聘副教授，博士生导师
教育工作经历
2021-01 至 今, 清华大学深圳国际研究生院, 生物医药与健康工程研究院, 副教授
2020-08 至 2020-12, 清华-伯克利深圳学院, 精准医学与公共健康研究中心, 副教授
2017-08 至 2020-07, 清华-伯克利深圳学院, 精准医学与公共健康研究中心, 研究员
2013-11至 2017-08, 英国牛津大学，博士后，导师：Hagan Bayley
2010-10 至 2013-10, 剑桥大学, 化学, 博士；Wilhelm Huck和Chris Abell
2009-10 至 2010-09, 剑桥大学, 化学, 硕士；Wilhelm Huck
2005-09 至 2009-07, 中山大学, 高分子材料与工程, 学士，导师：陈旭东
研究方向
类器官合成生物制造技术与应用研究
所获荣誉：
(1) 马少华(1/7); 日内瓦国际发明特别展金奖, 世界知识产权组织（WIPO）, 发明, 国际学术奖, 2022(马少华; 赵浩然; 蔡咏德; 李佳楠; 李家炜; 曹远雄; 杨浩威)
代表性论文
[1]. Ma, Shaohua*; Wang, Wanlong; Zhou, Jiaqi; Liao, Shangfeng; Hai, Cheng; Hou, Yibo; Zhou, Zhichun; Wang, Zitian; Su, Yingshi; Zhu, Yu; Dai, Xiaoyong; Zhao, Yuan; Liao, Sha; Cai, Yongde*; Xu, Xun*; Lamination-based organoid spatially resolved transcriptomics technique for primary lung and liver organoid characterization, PNAS, 2024, 121, e2408939121.
[2]. Yang, Haowei; Li, Jiawei; Zheng, Yichao; Cao, Yuanxiong; Zhu, Yu; Sang, Gan; Galan, Edgar A; Ruan, Chuqian; Ma, Wilson M. J.; Dai, Xiaoyong; Cai, Yongde*; Ma, Shaohua*; Ultra-small tissue-compatible organoid printer for rapid and controllable modeling of respiratory organoids, Device (Cell Press), 2024, 2, 100420.
[3]. Zheng, Yichao; Han, Fei; Wu, Zhengyu; Wang, Bingjie; Chen, Xingchi; Boulouis, Caroline; Jiang, Yuebin; Ho, Amanda; He, Dan; Sia, Wan Rong; Mak, Jeffrey Y.W.; Fairlie, David P.; Wang, Lin-Fa; Sandberg, Johan K.; Lobie, Peter E.; Ma, Shaohua*; Leeansyah, Edwin*; MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis, Science Advances, 2024, 10, eadn6331.
[4]. Zheng, Yichao; Tian, Qinyong; Yang, Haowei; Cai, Yongde; Zhang, Jiaxin; Wu, Yifen; Zhu, Shuo; Qiu, Zuocheng; Lin, Yimin; Hong, Jiangquan; Zhang, Yi; Dockrell, David; Ma, Shaohua*; Identification of nicotinic acetylcholine receptor for N-acetylcysteine to rescue nicotine-induced injury using beating cilia in primary tissue derived airway organoids, Advanced Science, 2024, 11, 2407054.
[5]. Zhou, Jiaqi; Huang, Yi-chun; Wang, Wanlong; Li, Jiawei; Hou, Yibo; Yi, Ziqi; Yang, Haowei; Hu, Keer; Zhu, Yu; Wang, Zitian; Ma, Shaohua*; Chronotoxici-plate containing droplet-engineered rhythmic liver organoids for drug toxicity evaluation, Advanced Science, 2024, 11, 2305925.
[6]. Liu, Hanghang; Xu, Haohan; Zhu, Yu; Wang, Zitian; Hu, Danni; Yang, Lingxiao; Zhu, Yinheng; Galan, Edgar A; Huang, Ruqi; Peng, Haiying; Ma, Shaohua *; A large model-derived algorithm for complex organoids with internal morphogenesis and digital marker derivation, Analytical Chemistry, 2024, 96, 19258-19266.
[7]. Feng, Yilin; Fan, Jiaqi; Cheng, Yifan; Dai, Qionghai; Ma, Shaohua*; Stress regulates Alzheimer's disease progression via selective enrichment of CD8+ T cells, Cell Reports, 2023, 42, 113313.
[8]. Cao, Yuanxiong; Tan, Jiayi; Zhao, Haoran; Deng, Ting; Hu, Yunxia; Zeng, Junhong; Li, Jiawei; Cheng, Yifan; Tang, Jiyuan; Hu, Zhiwei; Hu, Keer; Xu, Bing; Wang, Zitian; Wu, Yaojiong; Lobie, Peter E; Ma, Shaohua*; Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration, Nature Communications, 2022, 13, 7463.
[9]. Jiang, Shengwei; Zhao, Haoran; Zhang, Weijie; Wang, Jiaqi; Liu, Yuhong; Cao, Yuanxiong; Zheng, Honghui; Hu, Zhiwei; Wang, Shubin; Zhu, Yu; Wang, Wei; Cui, Shuzhong; Lobie, Peter E.; Huang, Laiqiang*; Ma, Shaohua*; An automated organoid platform with inter-organoid homogeneity and inter-patient heterogeneity, Cell Reports Medicine, 2020, 1, 100161.
[10]. Yong Wang, Mengqi Ji, Shengwei Jiang, Xukang Wang, Jiamin Wu, Feng Duan, Jingtao Fan, Laiqiang Huang, Shaohua Ma*, Lu Fang*, Qionghai Dai*, Augmenting vascular disease diagnosis by vasculature-aware unsupervised learning, Nature Machine Intelligence, 2020, 2, 337-346.
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